The Russian side moved into the Europa League after completing 3rd in their Champions League group prior to Christmas, behind Manchester United and Basel.
They are presently 3rd in the Russian League after 22 components, behind leaders Lokomotiv Moscow and second-placed Spartak Moscow.
When they beat Borussia Dortmund, Lazio will be positive of getting the much better of an RB Salzburg side that produced the shock of the last round.
RB Leipzig will play Marseille after conquering Zenit St Petersburg 3-2 on aggregate.
Leipzig are 6th in the Bundesliga table while Marseille taped a great 5-2 aggregate victory versus Athletic Bilbao in the round of 16.
The very first legs will be used 5th April with the return matches occurring one week later on.